DML
DML Sharif University of Technology
Hi-C interactions enrich for promoter interacting regions
Description
We have assessed this study to identify the elements that the promoters tend to interact with them more than other regions in DNA, which is a sign that they might have a function in the gene regulation process. We started studying the interactions between promoters and some known elements such as enhancers from chromHMM predicted elements and then examined some elements that are not proved to have interactions with a promoter, such as lncRNAs and heterochromatin regions. Then the GWAS variants were analyzed to study whether SNPs affect gene regulation or not.
Dataset
Details
Start Date
Status
95%
Contributors
Hamid R. Rabiee
Rassa Ghavami
Monireh Safari
Collaborators